François-René Alexandre: search on Z-Library

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1

Synthesis of Novel 1,3,4-Benzotriazepine Derivatives (VI)/(VII) and (X) from 4-Oxo-3,1-benzoxazine and 3,1-Benzothiazine-2-carbonitriles.

Francois-Rene Alexandre, Amaya Berecibar, Roger Wrigglesworth, Laurence Perreux, Jean Guillon, Jean-Michel Leger, Valerie Thiery, Thierry Besson

Journal:

Year:

2005

File:

PDF, 27 KB

2005

2

Synthesis and antiviral evaluation of carbocyclic nucleoside analogs of nucleoside reverse transcriptase translocation inhibitor MK-8591 (4’-ethynyl-2-fluoro-2’-deoxyadenosine)

Alexandre, François-René, Rahali, Rachid, Rahali, Houcine, Guillon, Sandra, Convard, Thierry, Fillgrove, Kerry L., Lai, Ming-Tain, Meillon, Jean-Christophe, Xu, Min, Small, James, Dousson, Cyril, Rahe

Journal:

Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 718 KB

english, 2018

3

ChemInform Abstract: A New Synthetic Route to β-Unsubstituted β-Lactones by Intramolecular Cyclization.

Francois-Rene Alexandre, Stephanie Legoupy, Francois Huet

Journal:

Year:

2000

File:

PDF, 30 KB

2000

4

ChemInform Abstract: Microwave-Assisted Niementowski Reaction. Back to the Roots.

Francois-Rene Alexandre, Amaya Berecibar, Thierry Besson

Journal:

Year:

2002

File:

PDF, 28 KB

2002

5

Novel Series of 8H-Quinazolino[4,3-b]quinazolin-8-ones via Two Niementowski Condensations.

Francois-Rene Alexandre, Amaya Berecibar, Roger Wrigglesworth, Thierry Besson

Journal:

Year:

2003

File:

PDF, 139 KB

2003

6

Efficient Synthesis of Thiazoloquinazolinone Derivatives.

Francois-Rene Alexandre, Amaya Berecibar, Roger Wrigglesworth, Thierry Besson

Journal:

Year:

2003

File:

PDF, 150 KB

2003

7

Stereoinversion of β- and γ-Substituted α-Amino Acids Using a Chemo-Enzymatic Oxidation—Reduction Procedure.

Alexis Enright, Francois-Rene Alexandre, Geoffrey Roff, Ian G. Fotheringham, Michael J. Dawson, Nicholas J. Turner

Journal:

Year:

2004

File:

PDF, 115 KB

2004

8

Synthesis of novel 1,3,4-benzotriazepine derivatives from 4-oxo-3,1-benzoxazine and 3,1-benzothiazine-2-carbonitriles

François-René Alexandre, Amaya Berecibar, Roger Wrigglesworth, Laurence Perreux, Jean Guillon, Jean-Michel Léger, Valérie Thiéry, Thierry Besson

Journal:

Year:

2005

Language:

english

File:

PDF, 272 KB

english, 2005

9

Novel series of 8H-quinazolino[4,3-b]quinazolin-8-ones via two Niementowski condensations

François-René Alexandre, Amaya Berecibar, Roger Wrigglesworth, Thierry Besson

Journal:

Year:

2003

Language:

english

File:

PDF, 225 KB

english, 2003

10

Amine–boranes: effective reducing agents for the deracemisation of dl-amino acids using l-amino acid oxidase from Proteus myxofaciens

François-René Alexandre, David P. Pantaleone, Paul P. Taylor, Ian G. Fotheringham, David J. Ager, Nicholas J. Turner

Journal:

Tetrahedron Letters

Year:

2002

Language:

english

File:

PDF, 111 KB

english, 2002

11

Microwave-assisted Niementowski reaction. Back to the roots

François-René Alexandre, Amaya Berecibar, Thierry Besson

Journal:

Tetrahedron Letters

Year:

2002

Language:

english

File:

PDF, 72 KB

english, 2002

12

Efficient synthesis of thiazoloquinazolinone derivatives

François-René Alexandre, Amaya Berecibar, Roger Wrigglesworth, Thierry Besson

Journal:

Tetrahedron Letters

Year:

2003

Language:

english

File:

PDF, 193 KB

english, 2003

13

Asymmetrization of meso-1,3-diols utilising Pseudomonas fluorescens lipase

François-René Alexandre, François Huet

Journal:

Tetrahedron: Asymmetry

Year:

1998

Language:

english

File:

PDF, 197 KB

english, 1998

14

Anticoagulation Therapy May Reverse Biliary Abnormalities Due to Acute Portal Thrombosis

Alexandre Louvet, Frederic Texier, Sebastien Dharancy, François-Rene Pruvot, Geraldine Sergent, Pierre Deltenre, Olivier Ernst, Jean-Claude Paris, Philippe Mathurin

Journal:

Digestive Diseases and Sciences

Year:

2006

Language:

english

File:

PDF, 664 KB

english, 2006

15

A New Synthetic Route to β-Unsubstituted β-Lactones by Intramolecular Cyclization

François-René Alexandre, Stéphanie Legoupy, François Huet

Journal:

Year:

2000

Language:

english

File:

PDF, 126 KB

english, 2000

16

Microwaves in drug discovery and multi-step synthesis

François-René Alexandre, Lisianne Domon, Stéphane Frère, Alexandra Testard, Valérie Thiéry, Thierry Besson

Journal:

Molecular Diversity

Year:

2003

Language:

english

File:

PDF, 116 KB

english, 2003

17

Structure-based design of a novel series of azetidine inhibitors of the hepatitis C virus NS3/4A serine protease

Parsy, Christophe, Alexandre, François-René, Brandt, Guillaume, Caillet, Catherine, Cappelle, Sylvie, Chaves, Dominique, Convard, Thierry, Derock, Michel, Gloux, Damien, Griffon, Yann, Lallos, Lisa, L

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 1.73 MB

english, 2014

18

Stereoinversion of ?- and ?-substituted ?-amino acids using a chemo-enzymatic oxidation?reduction procedure

Enright, Alexis, Alexandre, Francois-Rene, Roff, Geoffrey, Fotheringham, Ian G., Dawson, Michael J., Turner, Nicholas J.

Journal:

Chemical Communications

Year:

2003

Language:

english

File:

PDF, 105 KB

english, 2003

19

Synthesis and antiviral evaluation of a novel series of homoserine-based inhibitors of the hepatitis C virus NS3/4A serine protease

Alexandre, François-René, Brandt, Guillaume, Caillet, Catherine, Chaves, Dominique, Convard, Thierry, Derock, Michel, Gloux, Damien, Griffon, Yann, Lallos, Lisa, Leroy, Frédéric, Liuzzi, Michel, Loi,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 2.97 MB

english, 2015

20

Discovery and structural diversity of the hepatitis C virus NS3/4A serine protease inhibitor series leading to clinical candidate IDX320

Parsy, Christophe C., Alexandre, François-René, Bidau, Valérie, Bonnaterre, Florence, Brandt, Guillaume, Caillet, Catherine, Cappelle, Sylvie, Chaves, Dominique, Convard, Thierry, Derock, Michel, Glou

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 727 KB

english, 2015

21

Discovery of the Aryl-Phospho-Indole (IDX899), a highly potent anti-HIV non-nucleoside reverse transcriptase inhibitor

Dousson, Cyril, Alexandre, François-René, Amador, Agnès, Bonaric, Séverine, Bot, Stéphanie, Caillet, Catherine, Convard, Thierry, da Costa, Daniel, Lioure, Marie-Pierre, Roland, Arlène, Rosinovsky, El

Journal:

Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 483 KB

english, 2016

22

The discovery of IDX21437: design, synthesis and antiviral evaluation of 2’-α-chloro-2’-β- C -methyl branched uridine pronucleotides as potent liver-targeted HCV polymerase inhibitors

Alexandre, François-René, Badaroux, Eric, Bilello, John P., Bot, Stéphanie, Bouisset, Tony, Brandt, Guillaume, Cappelle, Sylvie, Chapron, Christopher, Chaves, Dominique, Convard, Thierry, Counor, Clém

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2017

Language:

english

File:

PDF, 532 KB

english, 2017

23

A Highly Diastereoselective Chloride-Mediated Dynamic Kinetic Resolution at Phosphorus On-Route to a Key Intermediate in the Synthesis of GSK2248761A

Ironmonger, Alan, Shipton, Mark, Slater, Fiona, Szeto, Pete, Unthank, Matthew G., Alexandre, François-René, Caillet, Catherine, Dousson, Cyril B.

Journal:

Tetrahedron Letters

Year:

2018

Language:

english

File:

PDF, 374 KB

english, 2018

24

Major hepatectomy for intrahepatic cholangiocarcinoma or colorectal liver metastases. Are we talking about the same story?

Doussot, Alexandre, Fuks, David, Regimbeau, Jean-Marc, Farges, Olivier, Sa-Cunha, Antonio, Pruvot, François-René, Adam, René, Navarro, Francis, Azoulay, Daniel, Heyd, Bruno, Pessaux, Patrick

Journal:

European Journal of Surgical Oncology (EJSO)

Year:

2019

File:

PDF, 290 KB

2019

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